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Synonyms for substantial issue in English

substantial issue
n
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Discover interesting words and their synonyms bad, said, storm, with, accommodation, family, prevalence, again, reward, mess, elevated, mix, tab, lineup, breath, combined, PC, better, repair, adult.
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Results may contain synonyms and analogies, related words that can be used in similar contexts.
Most frequent synonyms in English -1K, -2K, -3K, -4K, -5K, -10K, -20K, -30K, -40K, -50K, -60K, -70K, -80K, -90K, -100K, -110K, -120K, -130K, -140K, -150K.