Preferred polymers include biodegradable, amphiphilic polyphosphates which are capable of complexing one or more biologically active substances.
The two beta-diketone groups are capable of complexing a metal species.
Levels of HIV p24 and free complexing anti-p24 can be simultaneously determined for information of maximum prognostic significance.
Methods of complexing and quantitating a component in a sample such as urea or guanidine are also disclosed.